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Radula marginata Taylor |
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Radula marginata (Wairuakohu) is a species of plant in genus Radula[1], a genus of liverworts. It is endemic to New Zealand.[2][3] It has been found to contain cannabinoids.[4][5]
Cannabinoids[edit]
Radula Perrottetii Buy
Users smoking the plant have experienced different effects.[6][citation needed] The cannabinoid is not THC, the main psychoactive chemical in cannabis, but it is of similar molecular structure.[4] The liverwort contains perrottetinene and perrottetinenic acid.[4] The quantity of cannabinoid present is much less than in cannabis. Perrottetinene has been shown to be a moderately potent CB1 agonist leading to mild psychoactive effects in mice.[7]
Legal status[edit]
Generate dkim key pair. The liverwort grows as a common weed.[citation needed] Owning, growing and distributing the liverwort is legal.
Radula marginata may have been used in rongoā (Māori herbal medicine), but there is no firm evidence of this.
References[edit]
Liverwort For Sale
- ^Hussain, Tajammul; Espley, Richard V.; Gertsch, Jürg; Whare, Tracey; Stehle, Felix; Kayser, Oliver (2019). 'Demystifying the liverwort Radula marginata, a critical review on its taxonomy, genetics, cannabinoid phytochemistry and pharmacology'. Phytochemistry Reviews. 18 (3): 953–965. doi:10.1007/s11101-019-09638-8.
- ^http://www.discoverlife.org/mp/20l?id=GBIF2550163
- ^http://www.discoverlife.org/mp/20l?id=GBIF2550057
- ^ abcToyota, M.; et al. (2002). 'New bibenzyl cannabinoid from the New Zealand liverwort Radula marginata'(PDF). Chem Pharm Bull. 50 (10): 1390. doi:10.1248/cpb.50.1390.
- ^Hussain, Tajammul; Plunkett, Blue; Ejaz, Mahwish; Espley, Richard V.; Kayser, Oliver (2018). 'Identification of Putative Precursor Genes for the Biosynthesis of Cannabinoid-Like Compound in Radula marginata'. Frontiers in Plant Science. 9: 537. doi:10.3389/fpls.2018.00537. PMC5954354. PMID29868043.
- ^http://www.tripme.co.nz/forums/showthread.php?t=1943
- ^Chicca, A.; Schafroth, M. A.; Reynoso-Moreno, I.; Erni, R.; Petrucci, V.; Carreira, E. M.; Gertsch, J. (1 October 2018). 'Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high'. Science Advances. 4 (10): eaat2166. doi:10.1126/sciadv.aat2166. ISSN2375-2548. PMC6200358. PMID30397641.
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